NICOTINE USE DISORDER

This study looks at whether starting a quit attempt during the first half of the menstrual cycle (follicular phase) helps women stop smoking more successfully than starting during the second half (luteal phase) or without cycle timing. About 1,200 women who smoke daily and have r…

This study tests whether social media and a smartphone app can help teens and young adults stop vaping. Participants will be recruited through social media, screened by an online chatbot, and given a mobile app with tailored support to quit. The goal is to see if this approach he…

This study tests a gentle, non-invasive brain stimulation technique called temporal interference (TI) to see if it can reduce nicotine cravings and vaping. 120 adults who vape heavily will receive either real stimulation to a deep brain area or a sham (fake) treatment during a si…

This study aims to find the best spot in the brain to stimulate with magnetic pulses (TMS) to increase reward-related brain activity in smokers. Researchers will test different targeting methods in 36 nicotine-dependent adults across three sessions. The goal is to see which targe…

This study works with community organizations in Chicago to find out what makes it hard for people to quit smoking and what kind of help they need. Researchers will create a community advisory board and test a new smoking cessation program in a behavioral health center. The goal …

This study looks at how cooling ingredients like menthol and WS-23 affect how much adults like e-cigarettes and how addictive they might be. About 66 adults who currently vape will try different e-liquid flavors and report their experiences. The goal is to understand if these add…

This study aims to find the best way to use transcranial magnetic stimulation (TMS) to change how the brain processes rewards in people who are dependent on nicotine. Researchers will test different pulse patterns in 42 smokers to see which one most effectively alters a brain sig…