NICOTINE ADDICTION

This study compares two approaches to help adults stop using tobacco and lower their cancer risk. About 5,000 people who smoke will get either extra reminders and support or standard quit advice. The goal is to see which method leads to more people using medication, counseling, o…

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help people with schizophrenia quit or reduce smoking. Fifty adults who smoke at least 5 cigarettes daily will receive active rTMS using one of two c…

This pilot study tests whether semaglutide, a drug used for diabetes, can help adults with type 2 diabetes quit smoking when used alongside nicotine replacement therapy. About 100 participants will be followed for 6 months to see if the approach is feasible and effective. The goa…

This study enrolls 200 daily smokers aged 22+ to see if a virtual reality test can measure how much attention they pay to smoking cues. Half will take the medication varenicline and half a placebo for about two weeks. Researchers will track changes in eye gaze, cravings, and smok…

This study looks at how stopping smoking for six weeks affects the body's chemistry and gut bacteria in people with substance use disorders. Researchers will compare 100 participants who quit smoking with 50 healthy controls, using blood and stool samples along with psychological…

This study looks at how the amount of nicotine and the pH level in nicotine pouches change how they feel, how much people like them, and how addictive they might be. About 84 young adults who already use nicotine pouches will test different products in a lab setting. The goal is …