NEURODEVELOPMENTAL DISORDERS

This study tests a 16-week inclusive exercise program called PACE for adults with intellectual disability. Participants will attend fitness classes, meet with coaches, and use a web dashboard to set goals. The trial includes 376 people and will measure daily steps and moderate-to…

This study tests whether a daily probiotic supplement for 6 months can improve the balance of gut bacteria in children aged 3-7 who have neurodevelopmental disorders like autism and also suffer from gastrointestinal symptoms such as constipation or bloating. Sixty children will b…

This study compares a special program called COPCA with standard physical therapy and parent education for infants under 12 months who are at risk of developmental disorders. About 40 families will take part, with some receiving in-person or online COPCA coaching, others getting …

This study tests whether immersive virtual reality (VR) therapy can improve cognitive, motor, and social skills in children aged 8 to 18 with ADHD, autism, or cerebral palsy. Participants will use the CAREN VR system, which provides interactive exercises with visual, sound, and t…

This study tests a new approach called ENGAGE, where children with disabilities like autism or cerebral palsy help set their own therapy goals. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and one using usual therapy. Researchers wi…

This study looks at whether 'parentese' — the sing-song, high-pitched speech parents naturally use with babies — helps autistic children learn new words. Researchers will show videos or interact live with 100 children aged 18 to 59 months, some with autism and some without. They …

This study explores whether an advanced practice nurse can effectively screen for neurodevelopmental disorders (like learning or behavior problems) in children aged 1 to 5 who have congenital heart disease. Researchers will compare the nurse's screening results with a full assess…

This study follows 180 infants who had COVID-19 around birth to see if the infection affects hormone levels and development. Researchers focus on a temporary hormone surge called minipuberty, which is important for growth. By measuring hormones and developmental milestones, they …

This study looks at how children and adults with Developmental Coordination Disorder (DCD) sense touch and body position, and how they update their body image when using tools. Researchers will compare 280 participants with and without DCD to see if sensory deficits explain motor…

This study looks at whether brain activity recordings (EEG) taken before and after heart surgery in babies under 1 year old can predict later developmental issues like autism or attention problems. About 50 infants will be followed to see if early brain signals match their learni…

This study aims to better understand how children aged 8 to 16 with neurodevelopmental disorders (like autism or ADHD) process social information. Researchers will use a new set of tests to measure skills like recognizing emotions and understanding others' thoughts. The goal is t…

This study looks at whether a child-focused goal-setting approach called ENGAGE helps kids with neurodevelopmental disabilities do better in therapy. About 96 children aged 5-12 and their therapists will take part. Researchers will compare the ENGAGE method to usual care to see i…

This study tests a digital platform called the Genetics Navigator that helps patients and parents of children who are getting genetic testing. The goal is to see if using this tool reduces distress and improves the overall experience. About 170 adults and parents will use the pla…

This study watches how babies move in their first months to see if it predicts their development later. Researchers will video-record preterm and full-term infants and score their movements. When the children turn 18 and 36 months old, parents will fill out a questionnaire about …

This study aims to find out how many homeless people in France have autism, ADHD, or intellectual disability. Researchers will screen and diagnose 150 homeless adults living in shelters. The results could help create better support services for this group.

This study looks at how a 2-week, personalized therapy program helps children aged 4-12 with conditions like cerebral palsy, autism, or genetic disorders. Kids get about 2.5 hours of tailored therapy each day, focusing on skills like movement, attention, and communication. The go…

This study aims to create a tool that uses advanced sensors and machine learning to detect movement delays in babies as young as 1 month old. Researchers will observe 1,700 infants, including those with brain injuries and healthy babies, to see if the tool can accurately predict …

This study follows 1,000 people with genetic changes linked to brain development issues, such as autism, intellectual disability, and seizures. Researchers collect medical records, school reports, and questionnaires to learn how these gene variants affect thinking, movement, and …

This study looks at videos and sounds from babies to find early clues about conditions like cerebral palsy and autism. About 46 infants who were in the NICU will have their movements and cries recorded at home. Researchers hope to identify patterns that could lead to earlier dete…

This study looks at medical records of 1000 children with conditions like autism, epilepsy, and Down syndrome to find common biological patterns. Researchers want to understand what causes these disorders and how children respond to treatments. The goal is to improve diagnosis an…