Myofascial pain
Clinical trials for Myofascial pain explained in plain language.
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Scientists test new imaging to see muscle pain clearly
Diagnosis CompletedThis study aims to develop new imaging methods to better detect and understand myofascial pain, a common muscle pain condition. Researchers will compare 52 participants—some with myofascial pain and some healthy—using MRI, muscle electrical activity, and fiber-optic imaging. The …
Matched conditions: MYOFASCIAL PAIN
Sponsor: Washington University School of Medicine • Aim: Diagnosis
Last updated Sep 17, 2026 00:00 UTC
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Ultrasound reveals how jaw pain treatments change muscles
Symptom relief CompletedThis study looks at how two common treatments for myofascial jaw pain—a mouth splint and lidocaine injections—affect the muscles of the jaw and neck. Researchers use ultrasound to see changes in muscle structure, like how well the muscle fibers reflect sound waves. The goal is to…
Matched conditions: MYOFASCIAL PAIN
Sponsor: Istanbul Medipol University Hospital • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Botox vs. mouthguards: which eases grinding pain best?
Symptom relief CompletedThis study tested three ways to treat jaw pain caused by teeth grinding (bruxism): a custom mouthguard (occlusal splint), Botox injections, or both together. Sixty adults completed the 3-month trial. Researchers measured pain and jaw function changes to see which approach worked …
Matched conditions: MYOFASCIAL PAIN
Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Can botox beat ibuprofen for jaw pain from teeth grinding?
Symptom relief CompletedThis trial compares Botox injections with ibuprofen pills to see which better eases jaw muscle pain and improves quality of life in people with sleep bruxism (teeth grinding). Forty adults with jaw pain are randomly assigned to receive either Botox injections into the masseter an…
Matched conditions: MYOFASCIAL PAIN
Phase 4 • Sponsor: NEW Cyprus Health and Social Sciences University • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Can a few therapy sessions ease jaw pain and improve sleep?
Symptom relief CompletedThis study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…
Matched conditions: MYOFASCIAL PAIN
Sponsor: Ian Boggero, PhD • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Botox for jaw pain: ultrasound reveals muscle changes in teeth grinders
Symptom relief CompletedThis small study looked at 17 adults with bruxism (teeth grinding) who received Botox injections into their jaw muscle. Researchers used ultrasound to measure muscle thickness and texture before treatment, at 14 days, and at 90 days. They also tracked pain levels. The goal was to…
Matched conditions: MYOFASCIAL PAIN
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a cold tube ease pelvic pain? new study tests simple At-Home remedy
Symptom relief CompletedThis study tested whether placing a cold tube in the vagina for 10 minutes can reduce pelvic floor muscle pain in women. 165 women with pelvic pain used either a cold or room-temperature tube. Researchers measured pain changes right after use and after two weeks of daily use.
Matched conditions: MYOFASCIAL PAIN
Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New MRI method could unlock secrets of chronic muscle pain
Knowledge-focused CompletedThis study tests a new imaging method called MR Elastography to measure how muscles and their surrounding tissues move in people with myofascial pain syndrome. Researchers will compare results from 106 participants, including those with chronic pain and healthy volunteers. The go…
Matched conditions: MYOFASCIAL PAIN
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Study explores why some patients respond better to physical therapy
Knowledge-focused CompletedThis pilot study looked at 30 people with chronic neck or shoulder pain from myofascial pain syndrome. Researchers wanted to see if certain pain features (called nociplastic pain) affect how well patients respond to physical therapy. Participants were followed for 3 months after …
Matched conditions: MYOFASCIAL PAIN
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:16 UTC