MYELODYSPLASTIC SYNDROME (MDS)
Clinical trials for MYELODYSPLASTIC SYNDROME (MDS) explained in plain language.
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New pill aims to shrink spleens and ease symptoms in tough blood cancers
Disease control CompletedThis study tested an experimental pill called pelabresib, both alone and combined with an existing drug (ruxolitinib), for people with myelofibrosis and other blood cancers. The main goals were to find a safe dose and see if the treatment could reduce spleen size, ease symptoms l…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1, PHASE2 • Sponsor: Constellation Pharmaceuticals • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Supercharged cord blood offers new hope for cancer patients
Disease control CompletedThis study tested whether a new, lab-expanded cord blood transplant (called NiCord) works better than a standard cord blood transplant for patients with blood cancers like leukemia and lymphoma. The goal was to see if the expanded cells help patients recover their immune systems …
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE3 • Sponsor: Gamida Cell ltd • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New drug combo tested for Tough-to-Treat blood cancers
Disease control CompletedThis early-stage study tested a new drug called PRT2527, both by itself and combined with other cancer drugs, in people with advanced blood cancers that had returned or stopped responding to standard treatments. The main goals were to find a safe dose and see if the treatments sh…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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One donor, two transplants: experimental procedure aims to cure blood cancer and fix kidneys
Disease control CompletedThis pilot study tested a combined transplant from a partially matched family donor. It aimed to treat patients who had both a serious blood disorder (like leukemia) and advanced kidney disease at the same time. The goal was to cure the blood disorder and restore kidney function …
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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First human test of new blood disorder drug shows early safety profile
Knowledge-focused CompletedThis was an early-stage study to check the safety and see how the body handles a new drug called LP-001. It involved 68 healthy volunteers and tested single and multiple doses. The main goal was to see what side effects might occur and to measure how long the drug stays in the bl…
Matched conditions: MYELODYSPLASTIC SYNDROME (MDS)
Phase: PHASE1 • Sponsor: Longbio Pharma • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC