Myelodysplastic syndrome/acute myeloid leukemia
Clinical trials for Myelodysplastic syndrome/acute myeloid leukemia explained in plain language.
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Can adding another drug improve MDS treatment?
Disease control OngoingThis study compares the standard drug azacitidine alone versus azacitidine combined with either lenalidomide or vorinostat in 282 patients with higher-risk myelodysplastic syndromes (MDS) or chronic myelomonocytic leukemia (CMML). The goal is to see if any combination improves re…
Matched conditions: MYELODYSPLASTIC SYNDROME/ACUTE MYELOID LEUKEMIA
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Could removing certain immune cells prevent a deadly transplant complication?
Disease control OngoingThis study tests whether removing a specific type of immune cell (naive T cells) from donor stem cells can prevent chronic graft-versus-host disease (GVHD) in children and young adults with blood cancers. GVHD occurs when donor cells attack the patient's body after a stem cell tr…
Matched conditions: MYELODYSPLASTIC SYNDROME/ACUTE MYELOID LEUKEMIA
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Experimental Triple-Drug cocktail targets Hard-to-Treat leukemia
Disease control PausedThis early-phase trial tests whether adding regorafenib to the standard venetoclax and azacitidine regimen is safe and effective for people with acute myeloid leukemia (AML) that has returned or not responded to prior treatment. About 20 adults will receive the three-drug combina…
Matched conditions: MYELODYSPLASTIC SYNDROME/ACUTE MYELOID LEUKEMIA
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC