MUSCULOSKELETAL INJURY
Clinical trials for MUSCULOSKELETAL INJURY explained in plain language.
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New brace and rehab combo aims to get injured legs moving again
Disease control Recruiting nowThis study is testing whether a custom leg brace (called IDEO) combined with a special rehab program helps people with lower leg injuries move better. About 370 adults who already have the brace will do walking, stair, and other tests before, during, and after the program. The go…
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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Gel vs. pills: which pain relief works best for Kids' injuries?
Symptom relief Recruiting nowThis study is testing whether a pain-relief gel applied to the skin works as well as pain pills for children aged 6 to 18 with ankle or knee injuries. The goal is to see if a larger study is possible. Participants will use either the gel or the pills three times a day for three d…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: PHASE3 • Sponsor: University of Calgary • Aim: Symptom relief
Last updated May 26, 2026 04:36 UTC
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Antidepressant given right after injury may prevent PTSD and cut pain
Symptom relief Recruiting nowThis study tests whether giving fluoxetine (Prozac) immediately after a serious injury can prevent depression, PTSD, and reduce pain and opioid use. About 200 adults with fractures or other major trauma will receive either fluoxetine or a placebo for several months. Researchers w…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: PHASE4 • Sponsor: University of Florida • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Talking therapy may unlock pain relief for accident survivors
Symptom relief Recruiting nowThis study tests a type of talk therapy called Emotional Awareness and Expression Therapy (EAET) for people who have persistent pain after a serious bone or muscle injury. Researchers want to see if it's practical to run a larger study later. About 30 adults will attend weekly th…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 19, 2026 11:48 UTC
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Concussion's hidden danger: higher injury risk even after symptoms fade
Knowledge-focused Recruiting nowThis study looks at how a concussion changes the way people move, which may increase their risk for muscle and bone injuries. Researchers will compare 148 military members who have had a concussion with those who have not. The goal is to find movement problems that can be fixed w…
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Walter Reed National Military Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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5,000 athletes to help unlock secrets of ACL injuries
Knowledge-focused Recruiting nowThis study aims to build a database of normal movement patterns in healthy athletes aged 10 to 65. Researchers will track participants for 12 months to see who gets injured, especially ACL injuries. The goal is to better understand injury risk factors, not to test a treatment.
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Sanford Health • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Researchers test best heel height for ankle brace comfort
Knowledge-focused Recruiting nowThis study looks at how changing the heel height and stiffness of an ankle-foot brace (AFO) affects walking in people who use one daily. About 40 adults with leg injuries or nerve problems will walk with different heel cushions while researchers measure motion, comfort, and pain.…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC