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Antidepressant given right after injury may prevent PTSD and cut pain

NCT ID NCT06046859

First seen May 05, 2026 · Last updated May 20, 2026 · Updated 3 times

Summary

This study tests whether giving fluoxetine (Prozac) immediately after a serious injury can prevent depression, PTSD, and reduce pain and opioid use. About 200 adults with fractures or other major trauma will receive either fluoxetine or a placebo for several months. Researchers will track mood, pain levels, and recovery over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32608, United States

    Contact

Conditions

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