Muscle invasive bladder cancer
Clinical trials for Muscle invasive bladder cancer explained in plain language.
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Can intensified chemotherapy before surgery clear bladder tumors?
Disease control Stopped earlyResearchers test whether four cycles of dose-dense MVAC chemotherapy, given with G-CSF support, can shrink or eliminate muscle-invasive bladder cancer before radical surgery. The trial enrolls 24 adults with locally advanced urothelial carcinoma of the bladder who are fit for cis…
Matched conditions: MUSCLE INVASIVE BLADDER CANCER
Phase 2 • Sponsor: Pusan National University Yangsan Hospital • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Bladder cancer umbrella trial tests immunotherapy combos
Disease control Stopped earlyThis study tested several immunotherapy-based drug combinations in 272 people with advanced bladder cancer that had worsened after platinum chemotherapy. The goal was to see which combinations were safest and most effective at shrinking tumors or slowing the disease. Participants…
Matched conditions: MUSCLE INVASIVE BLADDER CANCER
Phase 1/2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Experimental bladder cancer drug shows promise but trial halted early
Disease control Stopped earlyThis study tested an experimental drug called enfortumab vedotin, alone or with other cancer drugs, in people with advanced bladder or urinary tract cancer. The goal was to see if the drug could shrink tumors and control the disease. The trial included 348 participants but was te…
Matched conditions: MUSCLE INVASIVE BLADDER CANCER
Phase 1/2 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New combo therapy shows promise for tough bladder cancer
Disease control Stopped earlyThis study tested whether adding the immunotherapy drug avelumab to standard radiation could help treat muscle-invasive bladder cancer in patients who cannot receive the usual chemotherapy. Fourteen participants received the combination therapy. The goal was to see if the cancer …
Matched conditions: MUSCLE INVASIVE BLADDER CANCER
Phase 2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can a simple urine test replace tumor biopsies for bladder cancer treatment?
Knowledge-focused Stopped earlyThis study looked at whether genetic changes found in urine could match those in tumor tissue for people with high-risk non-muscle invasive bladder cancer. The goal was to see if a urine test could help doctors choose the best immunotherapy for each patient. The study planned to …
Matched conditions: MUSCLE INVASIVE BLADDER CANCER
Sponsor: Hopital Foch • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC