MISMATCH REPAIR DEFICIENCY
Clinical trials for MISMATCH REPAIR DEFICIENCY explained in plain language.
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New pill plus immunotherapy shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests an experimental oral drug called Alintegimod (7HP349) combined with two immunotherapy drugs (ipilimumab and nivolumab) in people with advanced solid tumors like melanoma, lung, kidney, or liver cancer who have already tried other treatments. The goal is to see if…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: PHASE1, PHASE2 • Sponsor: 7 Hills Pharma, LLC • Aim: Disease control
Last updated May 26, 2026 11:11 UTC
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Immunotherapy before surgery may help remove Hard-to-Treat colon cancer
Disease control Recruiting nowThis study tests whether giving immunotherapy before surgery can help completely remove T4 colon cancer in people whose tumors have a specific DNA repair problem (dMMR). About 18 adults aged 18-75 with newly diagnosed, non-spread colon cancer will receive immunotherapy first, the…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 26, 2026 11:07 UTC
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Blood test could spot colon cancer before it spreads
Diagnosis Recruiting nowThis study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, precancerous polyps, and Lynch syndrome-related cancers early. Researchers will collect blood from 1,200 people who have already had a colonoscopy and see how accurate the test is…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Sponsor: San Raffaele University • Aim: Diagnosis
Last updated May 26, 2026 11:08 UTC
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AI helps cancer patients find the right clinical trial
Knowledge-focused Recruiting nowThis study is testing whether an artificial intelligence tool can help match cancer patients to clinical trials they might be eligible for. Researchers will enroll up to 50,000 people with various types of cancer and use the AI to suggest trials. The goal is to see if this approa…
Matched conditions: MISMATCH REPAIR DEFICIENCY
Sponsor: Massive Bio, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 11:16 UTC