MICROBIAL COLONIZATION

This study tests whether adding a pre-surgery scrub with isopropyl alcohol and chlorhexidine soap to the standard cleaning routine can lower the number of germs on the skin and reduce infections after elective foot and ankle surgery. About 100 adults having planned foot or ankle …

This study tests whether giving a newborn a nasal microbiome transplant from their parent can increase the diversity of bacteria in the baby's nose. The goal is to see if this can help prevent infections like those caused by Staphylococcus aureus. The study involves 175 premature…

This study looks at whether removing certain food additives (like carrageenan and polysorbates) from the diet can improve symptoms and gut health in people with moderately active ulcerative colitis. About 70 participants will be randomly assigned to either a normal healthy diet o…

This study tests whether a daily oral synbiotic (a mix of probiotics and prebiotics) can help women with a history of preterm birth carry their baby longer. About 400 pregnant women will take either the supplement or a placebo from early pregnancy. The goal is to see if the suppl…

This study aims to understand the natural bacteria living on the surface of the eye in both healthy people and those with certain eye conditions. Researchers will collect eye swabs from 500 adults in middle Tennessee to build a database of what a normal eye microbiome looks like.…

This early-stage study tests whether transferring nasal bacteria from a parent to a child can help restore the child's nasal microbiome after they've been treated with antibiotics for staph bacteria. About 175 children under 18 who have completed staph treatment will receive a na…

This study looks at how the drug bulevirtide changes gut bacteria and bile acids in people with hepatitis delta (a serious liver infection). Researchers will follow 20 patients for 48 weeks, collecting stool and blood samples to see how these changes relate to liver health. The g…

This study looks at how two common mouthwashes (Listerine and Lumineux Oral Essentials) change the bacteria and three viruses in your mouth and gut compared to rinsing with water. About 200 healthy adults aged 18-25 will rinse twice daily for 180 days. Researchers will collect mo…

This study looks at whether donor breast milk can help restore healthy gut bacteria in full-term babies born by C-section who need extra feeding. About 90 mothers and their infants will take part, with some babies getting donor milk and others getting formula. The goal is to see …