MICROBIAL COLONIZATION

This study looks at whether cleaning the mouth of very premature infants every 3-4 hours can reduce harmful bacteria and lower the risk of pneumonia and other breathing problems. Researchers will follow 40 infants born before 32 weeks and weighing less than 1500 grams, comparing …

This early study tests whether transferring a parent's healthy nasal bacteria to their newborn can help prevent staph infections. Researchers will give the baby a nasal spray containing the parent's bacteria or a placebo, then monitor the baby's nose bacteria and safety. The stud…

This study tests whether adding extra protein to breast milk during the first two weeks of life helps extremely premature infants (born at or before 28 weeks) gain more lean muscle and develop a healthier mix of gut bacteria. About 150 babies will be randomly assigned to get eith…

This study planned to test a treatment called MET-2, a mix of gut bacteria, to help clear antibiotic-resistant germs from the body after a bloodstream infection. It was designed for adults not in intensive care who had a resistant infection. The trial was withdrawn before enrolli…

This study looks at how eating pulses like beans and lentils changes the bacteria in your gut and affects your appetite. Researchers will measure gut microbes, appetite hormones, and other health markers in 44 overweight adults. Participants will eat a special diet and provide bl…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study aims to understand how the bacteria living in your body (the microbiome) influence recovery after surgery for pancreatic or related cancers. Researchers will collect saliva, blood, stool, and tumor samples from 200 adult patients before and after surgery. The goal is t…

This study looks at how the food babies eat changes the bacteria in their gut and how that relates to their growth and development. About 100 healthy breastfed infants, ages 4 to 7.5 months, will be observed as they start solid foods like sweet potato or pear. The goal is to unde…