Metastatic melanoma
Clinical trials for Metastatic melanoma explained in plain language.
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Can a DNA vaccine teach the immune system to hunt melanoma?
Disease control Not yet recruitingResearchers are testing whether adding an experimental DNA vaccine called iSCIB1+ to standard immunotherapy drugs nivolumab and ipilimumab helps people with advanced melanoma that cannot be removed by surgery. About 550 participants will be randomly assigned to receive either the…
Matched conditions: METASTATIC MELANOMA
Phase 3 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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New hope for advanced melanoma: immunotherapy combo tested in india
Disease control Not yet recruitingThis study tests a combination of two immunotherapy drugs, nivolumab and relatlimab, in people with advanced melanoma that hasn't been treated before. The goal is to see if the combination is safe and helps shrink tumors. About 30 adults and teens (ages 12 and up) in India will t…
Matched conditions: METASTATIC MELANOMA
Phase 4 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Cancer-Killing virus trial launches for melanoma that spread to brain
Disease control Not yet recruitingThis early-phase trial tests a virus called DNX-2401, designed to infect and destroy melanoma cells in the brain and body. About 50 adults with stage IV melanoma will receive injections to find the safest dose and number of treatments. The main goal is to check for side effects, …
Matched conditions: METASTATIC MELANOMA
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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A quest to find biomarkers that match melanoma patients with the right immunotherapy
Knowledge-focused Not yet recruitingThis study looks at whether clinical, pathological, and molecular features can predict how well people with metastatic melanoma respond to first-line immunotherapy. Researchers will collect and analyze data from about 200 patients treated at the European Institute of Oncology wit…
Matched conditions: METASTATIC MELANOMA
Sponsor: European Institute of Oncology • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Could a tiny skin shot replace harsh full-body immunotherapy for melanoma?
Knowledge-focused Not yet recruitingThis early-phase study tests whether a low-dose immunotherapy injection directly into the tumor can activate the immune system as effectively as standard high-dose treatment through the veins, but with fewer side effects. About 18 adults with advanced melanoma will receive either…
Matched conditions: METASTATIC MELANOMA
Phase 1/2 • Sponsor: Amsterdam UMC, location VUmc • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC