MELANOMA STAGE III
Clinical trials for MELANOMA STAGE III explained in plain language.
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New hope for controlling debilitating side effect of powerful cancer drugs
Disease control OngoingThis study is testing if a drug called infliximab is better than standard steroid treatment at resolving severe diarrhea and colon inflammation caused by immunotherapy drugs in people with advanced skin cancer. About 42 participants with stage III or IV skin cancer who develop th…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Apr 04, 2026 05:05 UTC
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New vaccine booster shots tested to supercharge melanoma treatment
Disease control OngoingThis study is testing whether adding one of two experimental cancer vaccines (SCIB1 or iSCIB1+) to standard immunotherapy drugs can improve outcomes for people with advanced, inoperable melanoma. The goal is to see if the vaccines help patients respond better to treatment and kee…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated Apr 04, 2026 05:05 UTC
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Custom cancer treatment: one shot before surgery decides Year-Long drug plan
Disease control OngoingThis study is testing a personalized approach to prevent melanoma skin cancer from coming back after surgery. Patients first receive a single dose of the drug nivolumab before their operation. Based on how well the tumor responds to that single dose, doctors then assign a specifi…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New copycat cancer drug faces keytruda in Head-to-Head test
Disease control OngoingThis study is testing whether a new biosimilar drug called FYB206 behaves similarly in the body to the established cancer drug Keytruda. The trial involves 96 patients with stage IIB/IIC or III melanoma who have had their cancer completely removed by surgery. Researchers want to …
Matched conditions: MELANOMA STAGE III
Phase: PHASE1 • Sponsor: Formycon AG • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug trial aims to unleash immune system against skin cancer
Disease control OngoingThis early-stage study is testing a new oral drug called SX-682 in people with advanced melanoma that has spread. The goal is to see if SX-682 can safely block certain cells that shield the tumor, allowing the patient's own immune system, boosted by an existing immunotherapy drug…
Matched conditions: MELANOMA STAGE III
Phase: PHASE1 • Sponsor: Syntrix Biosystems, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug duo aims to shrink tumors before melanoma surgery
Disease control OngoingThis study is testing whether giving two drugs—pembrolizumab and lenvatinib—for six weeks before surgery can better control stage III melanoma. The goal is to shrink the tumor and boost the body's immune response to improve long-term results after the operation. It involves 21 ad…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Melanoma Institute Australia • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New scan could predict if immunotherapy will wipe out melanoma before surgery
Disease control OngoingThis study is testing whether giving two immunotherapy drugs (nivolumab and ipilimumab) before surgery can shrink melanoma tumors and prevent the cancer from coming back. It involves 28 adults with stage III melanoma that can be surgically removed. The research also explores a ne…
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Double attack on melanoma: trial tests powerful drug combo before surgery
Disease control OngoingThis study compares two immunotherapy approaches given before surgery for advanced melanoma that can still be removed. Patients receive either one immunotherapy drug or a combination of two drugs for 6 weeks before their operation, followed by additional treatment afterward. The …
Matched conditions: MELANOMA STAGE III
Phase: PHASE2 • Sponsor: Diwakar Davar • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC