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Personalized immunotherapy after melanoma surgery shows promise in preventing return

NCT ID NCT04013854

First seen Nov 06, 2025 · Last updated May 18, 2026 · Updated 22 times

Summary

This study tests whether giving immunotherapy drugs (nivolumab alone or with ipilimumab) after melanoma surgery can prevent the cancer from coming back. The choice of treatment depends on how the tumor responds to a single dose of nivolumab before surgery. About 67 adults with stage III melanoma that can be removed surgically are participating. The goal is to improve recurrence-free survival while managing side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Duke Cancer Institute

    Durham, North Carolina, 27710, United States

  • Lancaster General Hospital

    Lancaster, Pennsylvania, 17601, United States

Conditions

Explore the condition pages connected to this study.