MDD
Clinical trials for MDD explained in plain language.
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Zapping depression away: new brain stimulation study offers hope
Disease control CompletedThis study tested whether a personalized form of non-invasive brain stimulation could better treat depression and loss of pleasure (anhedonia) in people who haven't responded to standard medications. Sixty adults with treatment-resistant depression received either a personalized …
Matched conditions: MDD
Phase: NA • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Headsets for healing: can VR make depression treatment better?
Symptom relief CompletedThis study tested whether using a virtual reality (VR) headset could help people with depression get more out of a common talk therapy. Researchers compared standard therapy to therapy enhanced with VR activities. The main goal was to see if the VR approach was practical, accepta…
Matched conditions: MDD
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Scientists use brain scans to 'Retrain' negative thoughts in depression
Symptom relief CompletedThis study tested a new therapy that uses real-time brain scans to help people with depression. While inside an MRI machine, participants received feedback about their brain activity related to negative attention patterns. The goal was to see if this high-tech 'brain training' co…
Matched conditions: MDD
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Generic patch tested for depression treatment
Knowledge-focused CompletedThis small study aimed to see if a new generic version of a selegiline skin patch gets into the bloodstream the same way as the existing brand-name patch (EMSAM®). It involved 12 healthy adults who each wore both patches at different times. Researchers measured drug levels in the…
Matched conditions: MDD
Sponsor: Corium Innovations, Inc. • Aim: Knowledge-focused
Last updated Mar 17, 2026 12:55 UTC