MASTECTOMY

This study tests if a safe green dye (ICG) can help surgeons find cancer-spreading lymph nodes through the same cut used for mastectomy, avoiding a second incision. About 90 women with breast cancer will receive the dye during surgery. The goal is to see if this method works as w…

This study tests whether a stellate ganglion block (a nerve injection in the neck) given before mastectomy can prevent depression and chronic pain after surgery. About 140 women with breast cancer will receive either the block or standard care. The goal is to see if this simple p…

This early study tests whether a special nerve-stimulating device can restore touch sensation to the breast area and reduce chronic pain in people who have had both breasts removed. Eight adults scheduled for mastectomy with reconstruction will take part. The goal is to see if th…

This study compares a new care pathway called AMADeuS, where women have awake mastectomy with immediate breast reconstruction and go home the same day, to standard hospital care. Researchers want to see if it controls pain just as well and is as safe during the first month after …

This study tests a 16-week video exercise program for breast cancer survivors who had surgery. Participants join small group classes online to improve fitness, balance, and strength. The goal is to see if the program is easy to follow and helps recovery.

This study tests whether giving lidocaine (a numbing medicine) through a vein during breast cancer surgery can prevent long-term pain. About 4,300 women having a mastectomy or lumpectomy will be randomly assigned to receive lidocaine or a placebo. The main goal is to see if fewer…

This study tests a new drain system called Interi against standard drains in women having implant-based breast reconstruction after mastectomy. The goal is to see if the new drain reduces complications, shortens drain time, and improves comfort. About 20 women will take part, and…

This study tests custom-designed 3D-printed molds to help surgeons shape breast tissue during reconstruction after mastectomy. The goal is to make the surgery more efficient and improve the final breast shape. About 160 adults having certain types of breast reconstruction will ta…

This study tests whether using opioid-free anesthesia during mastectomy can lower the chance of chronic pain one year after surgery. Researchers will compare this approach to standard opioid-based anesthesia in 230 breast cancer patients. Participants will be randomly assigned to…

This study tests a special sticky pad called Brijjit® to see if it can stop raised scars (hypertrophic scars) after gender-affirming mastectomy (top surgery). About 78 adults will take part, and each person will have the pad on one side of their chest while the other side gets no…

This study tests two different nerve-blocking techniques to see which one works better for pain after mastectomy (breast removal surgery). About 66 women having this surgery will receive one of the two blocks before the operation. Researchers will measure pain levels, how soon pa…

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy (breast removal surgery). About 150 women undergoing this surgery will be randomly assigned to one of three drug combinations. The goal is to s…