LYMPHATIC MALFORMATION
Clinical trials for LYMPHATIC MALFORMATION explained in plain language.
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Weekly pill may tame painful birthmarks with fewer side effects
Disease control Recruiting nowThis study tests whether taking the drug sirolimus once a week can safely shrink abnormal blood vessel growths (venous and lymphatic malformations) in people aged 2 and older. Current daily dosing causes many side effects, so researchers hope a weekly schedule will work just as w…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated May 26, 2026 07:27 UTC
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New injection could shrink painful cysts in kids without surgery
Disease control Recruiting nowThis study tests an injected medicine called TARA-002 for children aged 6 months to 18 years who have large fluid-filled cysts (lymphatic malformations). The goal is to see if up to 4 injections can safely shrink the cysts. About 38 children will take part.
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Protara Therapeutics • Aim: Disease control
Last updated May 26, 2026 07:27 UTC
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Could a common drug shrink rare facial growths in kids?
Disease control Recruiting nowThis study tests whether the drug rapamycin can shrink large, hard-to-treat lymphatic malformations in the face and neck of children. About 28 kids aged 0 to 18 will take rapamycin by mouth for 6 months. The goal is to see if the malformations shrink by at least one-fifth, improv…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Glow-in-the-Dark dye could make Children's tumor surgery safer and more effective
Disease control Recruiting nowThis study tests whether using a special dye (indocyanine green) that glows under a special camera can help surgeons better see and remove cystic lymphatic malformations in children. About 110 children with these fluid-filled lumps will be randomly assigned to either dye-guided s…
Matched conditions: LYMPHATIC MALFORMATION
Phase: NA • Sponsor: Nanjing Children's Hospital • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs for people with vascular malformations (abnormal blood or lymph vessels). Participants with slow-flow malformations and a specific gene mutation receive alpelisib, while those with fast-flow malformations and another mutation receive mirdametin…
Matched conditions: LYMPHATIC MALFORMATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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Scientists launch global registry to crack mysteries of rare lymphatic diseases
Knowledge-focused Recruiting nowThis study is creating a registry of up to 1,000 people with rare lymphatic anomalies—conditions that affect the body's lymph system. Researchers will collect information from medical records and yearly surveys to understand how these diseases progress, what treatments work, and …
Matched conditions: LYMPHATIC MALFORMATION
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 07:24 UTC