LUPUS NEPHRITIS
Clinical trials for LUPUS NEPHRITIS explained in plain language.
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Personalized dosing may boost lupus kidney remission
Disease control Not yet recruitingThis study tests whether adjusting the dose of an immunosuppressant drug (mycophenolate mofetil) based on regular blood tests helps more people with lupus kidney disease achieve remission. One hundred adults with active lupus nephritis will be randomly assigned to either standard…
Matched conditions: LUPUS NEPHRITIS
Phase: NA • Sponsor: Federal University of Maranhao • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Experimental CAR-T therapy takes on tough lupus kidney cases
Disease control Not yet recruitingThis study tests a new treatment called CRC01 for people with severe lupus that has caused kidney damage (lupus nephritis). CRC01 is made from the patient's own immune cells, which are modified to target and calm the overactive immune system. The trial will enroll 39 adults who h…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE1, PHASE2 • Sponsor: Curocell Inc. • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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Could a single infusion of supercharged immune cells tame tough lupus kidney disease?
Disease control Not yet recruitingThis study tests a new treatment called FT819 for people with severe lupus that has caused kidney damage (lupus nephritis). FT819 uses specially engineered immune cells from a donor to target and calm the overactive immune system. The main goal is to see if this therapy can resto…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE2 • Sponsor: Fate Therapeutics • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Engineered immune cells take aim at Hard-to-Treat lupus kidney disease
Disease control Not yet recruitingThis early study tests a new treatment called CHT105 for people with severe lupus that has not responded to standard therapies. CHT105 uses donor immune cells engineered to find and destroy the faulty immune cells driving the disease. The main goals are to check safety and see if…
Matched conditions: LUPUS NEPHRITIS
Phase: NA • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New drug shows promise for lupus kidney disease in early trial
Disease control Not yet recruitingThis study tests a new medicine, SIM0278, in 60 adults with active lupus nephritis, a kidney problem caused by lupus. Half will get the drug, half a placebo, and researchers will check if it helps improve kidney function over 52 weeks. The goal is to see if the drug is safe and w…
Matched conditions: LUPUS NEPHRITIS
Phase: PHASE2 • Sponsor: Simcere Pharmaceutical Co., Ltd • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Zinc deficiency linked to kidney damage in lupus patients?
Knowledge-focused Not yet recruitingThis study will check if people with lupus nephritis (kidney inflammation caused by lupus) have low zinc levels in their blood. Researchers will look at 75 patients to see if low zinc is connected to worse kidney function. The goal is to better understand the disease, not to test…
Matched conditions: LUPUS NEPHRITIS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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Blood test could replace painful kidney biopsies for lupus patients
Knowledge-focused Not yet recruitingThis study aims to find a better blood test to detect active kidney inflammation in people with lupus nephritis. Researchers will measure a specific antibody in the blood of 96 participants and compare it to results from kidney biopsies. The goal is to develop a less invasive way…
Matched conditions: LUPUS NEPHRITIS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:17 UTC