LUPUS ERYTHEMATOSUS, SYSTEMIC

This study is collecting real-world information on the long-term safety and effectiveness of the drug Saphnelo (anifrolumab) for people with systemic lupus. It involves over 1,600 patients whose lupus hasn't responded well to other available treatments. The main goal is to monito…

This study is testing an investigational drug called litifilimab to see if it can better control disease activity in adults with active systemic lupus erythematosus (SLE). Participants, who are already taking standard lupus medications, receive either litifilimab or a placebo inj…

This study aims to learn about the long-term safety and side effects of the drug cenerimod for adults with moderate-to-severe lupus. It will follow about 680 people who took part in earlier trials, giving them cenerimod along with their standard lupus medications for up to 3 year…

This study is testing an investigational drug called litifilimab for adults with active systemic lupus erythematosus (SLE). The goal is to see if adding monthly injections of litifilimab to a patient's standard lupus medications can better control the disease, reduce symptom flar…

This study is testing if a new oral drug called cenerimod helps control symptoms when added to standard treatments for adults with moderate-to-severe lupus. About 420 participants will take either cenerimod or a placebo pill daily for one year, while continuing their usual lupus …

This study aims to understand if depression makes it harder for teens and young adults with lupus to keep up with their medical appointments and treatment. Researchers are also testing a specially designed mobile phone app to see if it's a helpful and practical tool for improving…

This study is testing whether a Pilates exercise program can help women with lupus feel better. Researchers want to see if the exercises can reduce common problems like fatigue, pain, poor sleep, and low mood, and improve overall quality of life. The study will compare a group do…

This study is testing whether a drug called memantine can safely help with the memory and thinking problems (often called 'brain fog') that many people with lupus experience. For 14 weeks, 111 participants with lupus and measured cognitive impairment will receive either memantine…

This research study aims to understand how autoimmune diseases like lupus develop by comparing immune cells from people with autoimmune conditions, people with infectious diseases, and healthy individuals. Researchers will collect blood and sometimes bone marrow samples from 2,50…