LUPUS ERYTHEMATOSUS, SYSTEMIC

This study tests a new drug called litifilimab for people with active systemic lupus erythematosus (SLE), a chronic autoimmune disease. About 562 adults already on standard lupus treatments will receive either litifilimab or a placebo as a shot every 4 weeks for a year. The goal …

This study tests whether adding cenerimod to standard lupus treatments can better control symptoms in adults with moderate-to-severe systemic lupus erythematosus (SLE). About 470 participants will receive either cenerimod or a placebo for 12 months. The goal is to see if cenerimo…

This study tests whether adding cenerimod to standard lupus treatments can better control symptoms in adults with moderate-to-severe lupus. About 451 participants will receive either cenerimod or a placebo for 12 months. The goal is to see if cenerimod reduces disease activity wi…

This study looks at the long-term safety of cenerimod in adults with moderate-to-severe systemic lupus erythematosus (SLE). About 680 participants who completed a previous year-long study will take cenerimod on top of their usual lupus medications for up to 3 years. Researchers w…

This study tests a new drug called litifilimab for people with active systemic lupus erythematosus (SLE), a chronic autoimmune disease. About 548 adults already on standard lupus treatments will receive either litifilimab or a placebo as a shot every 4 weeks for a year. The goal …

This study follows 1620 lupus patients who are not responding well to current treatments to see how safe and effective Saphnelo (anifrolumab) is over the long term. Researchers will monitor for side effects like infections and allergic reactions. The goal is to gather real-world …

This study looks at whether clinical Pilates exercises can help women with lupus feel less tired, improve their mood, sleep better, and have a better quality of life. About 30 women with stable, low-activity lupus will take part. The goal is to see if this gentle exercise program…

This study tests whether personalized coaching on physical activity and nutrition can reduce fatigue in people with lupus. 200 participants are split into two groups: one gets coaching on exercise and diet, the other gets general lupus education. The goal is to see if the coachin…

This study tests an online program designed to help people with inflammatory arthritis stay employed. About 528 adults with conditions like rheumatoid arthritis or lupus will either use the program or receive standard care and printed materials. The program includes eLearning and…

This study looks at how depression symptoms, like loss of interest, may cause teens and young adults with lupus to skip medical appointments. Researchers will test a mobile health app designed to improve clinic attendance and mood. About 40 participants aged 15-24 from the Bronx …

This study looks at immune cells from people with autoimmune diseases, infectious diseases, and healthy volunteers. Researchers want to understand how these cells differ. The goal is to learn more about how the immune system works in different conditions. Up to 2,500 people will …