LUNG DISEASES

This program provided access to the experimental drug taletrectinib for patients with advanced ROS1-positive lung cancer who had run out of approved treatment options and couldn't join regular clinical trials. The program was designed for people whose cancer had spread and who co…

This study aimed to test how well a special catheter device works for delivering clot-dissolving medicine directly to blood clots in the lungs. It planned to enroll up to 10 adults with serious but not life-threatening lung clots. The main goals were to see if the device helped c…

This study aims to learn about the long-term safety and effectiveness of the drug ralinepag for adults with pulmonary arterial hypertension (PAH), a serious lung and heart condition. It is an extension study for about 1,000 people who have already taken ralinepag in a previous cl…

This study is observing how well a combination of the drug Osimertinib and standard chemotherapy works for people with a specific type of advanced lung cancer (EGFR-positive NSCLC) in a real-world setting. It involves 532 adult patients who have already started this specific trea…

This study is testing a new medical device called the Aventus Thrombectomy System. It is designed to physically remove dangerous blood clots from the lungs of patients with a sudden, severe pulmonary embolism. The trial will enroll 130 adults to see if the procedure is safe and e…

This study is testing whether an inhaled drug called mosliciguat is safe and effective for people who have high blood pressure in their lungs (pulmonary hypertension) caused by underlying lung scarring (interstitial lung disease). About 135 participants will be randomly assigned …

This study is testing whether a combination of fish oil (Lovaza) and curcumin (from turmeric) can help reduce the size of small lung nodules found in former and current heavy smokers. The goal is to see if these natural supplements might help prevent lung problems before they bec…

This study aims to collect recordings of normal and abnormal lung sounds from up to 750 adult patients. Doctors will use special digital stethoscopes during regular check-ups to gather these sounds. The recordings will be used to train a computer program (an AI algorithm) to bett…

This study aims to see if providing standardized training to cancer doctors in smaller city and county hospitals leads to better testing and treatment for patients with advanced non-small cell lung cancer. It will follow 1,000 patients to measure if doctors order more recommended…

This study aims to understand how diseases in the lungs, digestive system, or endocrine (hormone) glands affect brain activity over time. Researchers will use a special type of brain scan (PET/CT) on 200 participants to see if changes in brain energy use can predict future health…

This study aims to understand why lung disease varies so much in people with cystic fibrosis (CF), even when they have the same genetic mutation. Researchers are analyzing the DNA of 600 CF patients to identify other genes that might make the lung disease milder or more severe. T…