LUNG DISEASES

This study tested an investigational drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if vapendavir could reduce lower respiratory symptoms like cough, wheezing, and shortness of breath after they were exposed to a common cold virus (rhi…

This study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …

This study looked at whether taking vitamin D every day can lower the risk of serious lung problems in children and teens with sickle cell disease. Lung issues like infections and acute chest syndrome are major causes of illness in this group. The study involved 58 participants a…

This study tested whether a simple checklist called the YEARS algorithm can safely rule out dangerous blood clots in the lungs (pulmonary embolism) in cancer patients, reducing the need for CT scans. Researchers compared the YEARS approach to standard CT scanning alone in 698 adu…

This study tested whether giving lidocaine or alfentanil before inserting a bronchoscope (a tube used to examine the lungs) can prevent coughing when numbing medicine is sprayed. Coughing during the procedure can cause problems like low oxygen or heart issues. 108 adults having l…

This study tested a nerve-freezing technique (cryoanalgesia) during robot-assisted lung surgery to see if it reduces pain afterward. 33 adults having lung surgery were randomly assigned to receive the nerve block or not. Researchers measured pain scores and pain medication use fo…

This study looked at whether people with pulmonary arterial hypertension (PAH) have low carnitine levels and if taking carnitine supplements could help. Ten adults with PAH completed the study, which measured carnitine in their diet and blood over several weeks. The goal was to g…

This study looked at whether firefighters have different lung scan results compared to non-firefighters, and if a blood test can help predict lung cancer risk. Researchers enrolled 734 current and retired firefighters to compare their low-dose CT scans with those of matched contr…

This study looked at whether a coordinated team approach to managing sedative drugs could reduce the number of days children with acute respiratory failure need a breathing machine. Over 2,400 children from age 2 weeks to 18 years participated. The goal was to find better ways to…

This study tested a new device called Neola® that monitors the lungs of newborn babies, especially those born early. Ten preterm or full-term infants were involved to see if the device is safe and works well. The main goal was to check for any side effects, like skin reactions, w…

This study tested a new navigation device for lung biopsies in 37 adults. The goal was to see if the device is easy for doctors to use and if a very low-dose CT scan can accurately confirm that the biopsy tool is in the right spot. Participants had a bronchoscopy with the new dev…

This study tested whether a new, thinner freezing probe (cryoprobe) works better than the usual forceps for taking lung tissue samples during a bronchoscopy. About 500 adults with lung disease took part. The main goal was to see which tool leads to a clear diagnosis more often, w…

This study looked at whether a person's blood group antigens are connected to asthma attacks. Researchers followed 126 people with asthma to see if certain blood types had more flare-ups needing steroids. The goal was to understand, not to test a new treatment.