LOW-GRADE GLIOMA
Clinical trials for LOW-GRADE GLIOMA explained in plain language.
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New hope for kids with Hard-to-Treat cancers: targeted drug shows promise
Disease control CompletedThis study tested a drug called tazemetostat in 20 children whose cancers had come back or weren't responding to treatment. The children had specific gene changes (EZH2, SMARCB1, or SMARCA4) in their tumors. The goal was to see if the drug could shrink or slow the growth of these…
Matched conditions: LOW-GRADE GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 18, 2026 11:50 UTC
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New hope for kids with tough brain tumors: experimental drug shows promise in early trial
Disease control CompletedThis early-phase study tested a drug called Tovorafenib in 44 children with low-grade gliomas (a type of brain tumor) that had come back or continued growing despite other treatments. The main goal was to find the safest dose and check for side effects. The drug works by blocking…
Matched conditions: LOW-GRADE GLIOMA
Phase: PHASE1 • Sponsor: Karen D. Wright, MD • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New imaging agent could sharpen detection of recurrent brain tumors
Diagnosis CompletedThis study tested a special dye called fluoroethyltyrosine (FET) used during a PET scan to see if it can better detect brain tumors that have come back. Researchers enrolled 143 people with different types of brain tumors. The goal was to see how accurate the FET PET scan is at f…
Matched conditions: LOW-GRADE GLIOMA
Phase: PHASE2 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated Jun 02, 2026 11:40 UTC
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New brain scan may sharpen surgery and radiation for glioma patients
Knowledge-focused CompletedThis study tested whether a special PET scan called 18F-FDOPA can help doctors better plan surgery and radiation for people with brain tumors (gliomas). Twenty-four adults with newly diagnosed high- or low-grade glioma took part. The scan was compared with standard MRI and tissue…
Matched conditions: LOW-GRADE GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:04 UTC