LOCALLY ADVANCED RECTAL CANCER (LARC)
Clinical trials for LOCALLY ADVANCED RECTAL CANCER (LARC) explained in plain language.
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New combo could spare rectal cancer patients from radiation side effects
Disease control OngoingThis study tests a new approach for people with a common type of locally advanced rectal cancer (MSS/pMMR). Instead of standard radiation, participants receive a combination of chemotherapy (mFOLFOX6) and an immunotherapy drug (PD-1 antibody) before surgery. The goal is to shrink…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: NA • Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated May 26, 2026 11:39 UTC
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New drug cocktail aims to shrink rectal tumors before surgery
Disease control OngoingThis study tests whether adding two immune-boosting drugs (PCSK9 and PD-1 inhibitors) to standard chemoradiation can help shrink tumors in people with a specific type of advanced rectal cancer. About 30 adults aged 18-75 with no distant spread are taking part. The goal is to see …
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated May 26, 2026 11:24 UTC