LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug aims to stop head and neck cancer's return after chemo-radiation
Disease control Recruiting nowThis study tests a new drug called volrustomig in people with advanced head and neck cancer that hasn't spread. Participants have already completed standard chemoradiation and their cancer hasn't grown. The trial compares receiving volrustomig versus just being watched to see if …
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 26, 2026 04:25 UTC
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New drug cocktail shows promise in head and neck cancer fight
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (pucotenlimab) to a targeted therapy (MRG003) before standard chemoradiation can shrink tumors more effectively in people with advanced head and neck cancer. About 106 adults aged 18-75 will take part. Half will get the drug c…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Groupe Oncologie Radiotherapie Tete et Cou • Aim: Disease control
Last updated May 26, 2026 04:24 UTC
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New hope for elderly cancer patients: radiation-boosting injection tested in major trial
Disease control Recruiting nowThis study tests a new drug called NBTXR3 that is injected into tumors to make radiation therapy more effective. It is for adults aged 60 and older with advanced head and neck cancer who cannot receive standard chemotherapy. The trial will compare the combination of NBTXR3 plus r…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated May 26, 2026 04:24 UTC
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Could smaller surgery after immunotherapy spare head and neck cancer patients?
Disease control Recruiting nowThis study compares a less extensive surgery (de-escalated) to standard surgery for people with advanced head and neck cancer who have already responded well to immunotherapy and chemotherapy. The goal is to see if the smaller surgery can control the cancer just as well while imp…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Qunxing Li,MD • Aim: Disease control
Last updated May 26, 2026 04:19 UTC
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New drug combo aims to boost radiation therapy for head and neck cancer
Disease control Recruiting nowThis early-phase trial tests whether adding the experimental drug ipatasertib to standard chemotherapy and radiation is safe for people with advanced head and neck cancer. Ipatasertib may help stop cancer cells from growing. About 46 adults with certain types of head and neck can…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps the immune syst…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New combo therapy aims to shrink head and neck tumors before surgery
Disease control Recruiting nowThis study tests whether giving low-dose radiation along with an immunotherapy drug before surgery can help shrink tumors in people with advanced head and neck cancer. About 22 adults with surgically removable cancer will receive this combination, then have surgery. The goal is t…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Xiwei XU • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Promising new combo could shrink head and neck tumors before surgery
Disease control Recruiting nowThis study tests whether adding a targeted drug (becotatug vedotin) to standard immunotherapy works better than immunotherapy alone for people with a certain type of advanced head and neck cancer that can be removed by surgery. About 430 adults with EGFR-positive, CPS≥1 tumors wi…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Ming-Yuan Chen • Aim: Disease control
Last updated May 20, 2026 11:53 UTC