Locally advanced head and neck squamous cell carcinoma
Clinical trials for Locally advanced head and neck squamous cell carcinoma explained in plain language.
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Radiation plus targeted antibody tested in older head and neck cancer patients
Disease control Not yet recruitingResearchers are testing whether adding nimotuzumab to intensity-modulated radiation therapy helps older adults with locally advanced head and neck squamous cell carcinoma who cannot tolerate standard chemotherapy. The study enrolls patients aged 65 and older with EGFR-positive tu…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase 2 • Sponsor: Ke Hu • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Cutting radiation after surgery: a new hope for head and neck cancer patients?
Disease control Not yet recruitingThis trial is testing whether giving a lower dose of radiation after surgery can be as effective as the standard dose for people with advanced head and neck cancer. Participants first receive chemotherapy and immunotherapy before surgery, and then the radiation plan is tailored b…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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New combo therapy aims to shrink head and neck tumors before surgery
Disease control Not yet recruitingThis study tests whether giving radiation along with immunotherapy before surgery works better than immunotherapy alone for people with advanced head and neck cancer. About 36 adults with treatable but advanced cancer will be split into two groups. The goal is to see if the combi…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase 2 • Sponsor: Chen Chunyan • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New imaging agent could sharpen cancer treatment decisions
Diagnosis Not yet recruitingThis early-phase study will test a new radioactive tracer called [18F]-AraG in just 5 people with advanced head and neck cancer. Participants will receive two PET/CT scans (before and during standard chemoradiotherapy) to see if the tracer's uptake matches immune cell activity an…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Early phase 1 • Sponsor: Indiana University • Aim: Diagnosis
Last updated Jul 24, 2026 00:00 UTC