LOCALLY ADVANCED COLORECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED COLORECTAL CARCINOMA explained in plain language.
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New drug combo hopes to shrink Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase study tests a combination of two drugs—trifluridine/tipiracil (a chemotherapy) and talazoparib (a targeted therapy)—in people with advanced colorectal or gastroesophageal cancers that have spread. The main goals are to find the safest dose and understand side eff…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Could adding immunotherapy to chemotherapy shrink colorectal tumors better?
Disease control Recruiting nowThis study tests whether adding immune checkpoint inhibitors to standard chemotherapy before surgery can improve outcomes for people with locally advanced colorectal cancer. About 170 adults with stage II/III colorectal cancer will be randomly assigned to receive either the combi…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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Glow-in-the-dark surgery targets hidden cancer cells in colorectal patients
Disease control Recruiting nowThis study tests a two-step approach for people with advanced or returning colorectal cancer. First, a special drug makes cancer cells glow during surgery, helping surgeons remove more of them. Then, a laser activates the drug to kill any remaining cancer cells. The goal is to im…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Could a common drug help cancer patients regain appetite and weight?
Symptom relief Recruiting nowThis study tests whether olanzapine, a drug that affects brain chemicals, can help people with advanced cancer who are losing weight and appetite. About 66 adults with certain cancers (like lung, stomach, or colon) will receive either olanzapine or a placebo. The goal is to see i…
Matched conditions: LOCALLY ADVANCED COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated May 26, 2026 10:13 UTC