LOCALLY ADVANCED BREAST CANCER (LABC)
Clinical trials for LOCALLY ADVANCED BREAST CANCER (LABC) explained in plain language.
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New hope for hard-to-treat breast cancer: combo therapy enters human trials
Disease control Not yet recruitingThis study tests a new combination of two drugs (JSKN016 and D-0502) in 60 people with advanced hormone receptor-positive, HER2-negative breast cancer that has worsened after standard hormone therapy. The goal is to see if the combo is safe and shrinks tumors. Participants receiv…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd • Aim: Disease control
Last updated May 26, 2026 06:04 UTC
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New drug cocktail aims to shrink Hard-to-Treat breast tumors before surgery
Disease control Not yet recruitingThis study tests a new combination of drugs (pyrotinib, darcilib, and standard hormone therapy) given before surgery to people with a common type of breast cancer (HR+HER2 low). The goal is to see if this approach shrinks tumors more effectively. About 33 participants will receiv…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Pre-Surgery shoulder stretches may ease pain after mastectomy
Symptom relief Not yet recruitingThis study looks at whether doing shoulder range-of-motion exercises for 6-8 weeks before a mastectomy can lower inflammation, reduce pain, and improve shoulder function and quality of life afterward. About 52 adults with advanced breast cancer will take part. The goal is to see …
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Indonesia University • Aim: Symptom relief
Last updated May 26, 2026 05:51 UTC
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Mind over tumor: therapy may boost chemo power in breast cancer
Symptom relief Not yet recruitingThis study tests whether a brief psychological therapy called Acceptance and Commitment Therapy (ACT) can improve how well chemotherapy works in women with locally advanced breast cancer. About 54 participants will either receive standard chemotherapy alone or with added ACT sess…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Phase: NA • Sponsor: Universitas Airlangga • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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Lab-Grown tumors could unlock secrets of chemo resistance in breast cancer
Knowledge-focused Not yet recruitingThis study aims to understand why some breast cancers resist chemotherapy. Researchers will grow miniature 3D tumor models (organoids) from patient tissue samples and test how they respond to drugs. By linking lab results to actual patient outcomes, they hope to find ways to pred…
Matched conditions: LOCALLY ADVANCED BREAST CANCER (LABC)
Sponsor: Atlas University • Aim: Knowledge-focused
Last updated May 26, 2026 05:51 UTC