LI-FRAUMENI SYNDROME
Clinical trials for LI-FRAUMENI SYNDROME explained in plain language.
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New registry aims to unlock secrets of rare cancer syndrome
Knowledge-focused Recruiting nowThis study is a registry that gathers medical, genetic, and quality-of-life information from people with Li-Fraumeni syndrome or similar conditions. The goal is to better understand how the disease develops and progresses over time. No treatments or experimental drugs are given. …
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 08:00 UTC
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Massive heart study seeks 5,000 volunteers to uncover hidden risks
Knowledge-focused Recruiting nowThis study aims to learn more about heart and blood vessel diseases by observing people who have them or are at risk. Researchers will collect blood, tissue, and perform imaging tests like MRI and CT scans. The goal is to improve diagnosis and understanding of these conditions. P…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 26, 2026 07:59 UTC
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Why do people say yes or no to genetic counseling trials?
Knowledge-focused Recruiting nowThis study looks at why people with Li-Fraumeni syndrome might choose to join or not join a future trial that compares standard genetic counseling with a more personalized approach. Researchers will ask 500 participants about their willingness to take part. The goal is to underst…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 07:51 UTC
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Massive study aims to unlock secrets of rare Cancer-Predisposing syndrome
Knowledge-focused Recruiting nowThis study follows up to 5,000 people with Li-Fraumeni syndrome (LFS), a genetic condition that raises the risk for several cancers. Researchers collect medical and family history, blood samples, and questionnaires to better understand how TP53 gene changes and other factors affe…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Massive study aims to unlock secrets of rare Cancer-Predisposing gene
Knowledge-focused Recruiting nowThis study is collecting information and samples from 1,500 people who have changes in the TP53 gene, which can increase the risk of cancer. The goal is to better understand Li-Fraumeni Syndrome and other conditions linked to TP53. Participants include people with known TP53 muta…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Hunt for hidden cancer genes in families
Knowledge-focused Recruiting nowThis research study aims to discover new genes that may increase the risk of childhood cancer. Researchers will collect blood samples and health information from 1,500 people in families where cancer clusters. The goal is to build a registry and sample bank to help future diagnos…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC