Massive study aims to unlock secrets of rare Cancer-Predisposing syndrome
NCT ID NCT01443468
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times
Summary
This study follows up to 5,000 people with Li-Fraumeni syndrome (LFS), a genetic condition that raises the risk for several cancers. Researchers collect medical and family history, blood samples, and questionnaires to better understand how TP53 gene changes and other factors affect cancer risk. The goal is to improve early detection and care, not to test a new treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Cancer Institute - Shady Grove
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.