LI-FRAUMENI SYNDROME
Clinical trials for LI-FRAUMENI SYNDROME explained in plain language.
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What makes people join a genetic counseling study? researchers want to find out
Knowledge-focused Recruiting nowThis study asks 500 people with Li-Fraumeni syndrome (or their parents) to fill out a questionnaire about why they would or would not join a future trial comparing standard genetic counseling to a personalized version. The goal is to understand what factors influence their decisi…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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Hunt for hidden cancer genes: families needed to unlock hereditary secrets
Knowledge-focused Recruiting nowThis study aims to discover new genes that may cause certain cancers to run in families. Researchers will collect blood samples and health information from 1,500 people in families where multiple members have had cancer, especially childhood cancers. The goal is to build a regist…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:03 UTC
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Massive heart study seeks 5,000 volunteers to uncover hidden risks
Knowledge-focused Recruiting nowThis study aims to learn more about heart and blood vessel diseases by observing people who have them or are at risk. Researchers will collect samples and perform tests like imaging and stress tests on up to 5,000 participants, including healthy volunteers and relatives of affect…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:51 UTC
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Scientists seek clues to rare cancer syndrome in 5,000-Person study
Knowledge-focused Recruiting nowThis study aims to learn more about Li-Fraumeni syndrome (LFS), a genetic condition that raises the risk of several cancers. Researchers will study up to 5,000 people with LFS or related cancer histories to find new genes, understand how the TP53 gene works, and identify factors …
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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New registry aims to unlock secrets of rare cancer syndrome
Knowledge-focused Recruiting nowThis study is creating a registry of people with Li-Fraumeni syndrome, a rare genetic condition that increases the risk of several cancers. Researchers will collect medical, genetic, and quality-of-life information from up to 200 participants in Italy. The goal is to better under…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:09 UTC
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Massive study aims to unlock secrets of rare Cancer-Predisposing gene
Knowledge-focused Recruiting nowThis study is collecting information and samples from 1,500 people with TP53 gene changes (linked to Li-Fraumeni Syndrome, a condition that raises cancer risk) and their relatives. Researchers want to better understand how these gene variants affect cancer risk and how accurate f…
Matched conditions: LI-FRAUMENI SYNDROME
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:09 UTC