LEUKEMIA, MYELOID, ACUTE

This study tested whether adding pevonedistat to standard azacitidine helps people with certain blood cancers (MDS, CMML, or low-blast AML) live longer without their disease getting worse. About 450 adults at high risk of progression took part. The goal was to see if the combinat…

This study tested a combination of two drugs, azacitidine and venetoclax, in 40 adults aged 45 to 65 with newly diagnosed acute myeloid leukemia (AML). The goal was to see if the combo is safe and effective at shrinking or eliminating the cancer. Participants received the drugs i…

This study tested a new drug, liposomal annamycin, combined with a standard chemotherapy (cytarabine) in 22 adults with acute myeloid leukemia (AML). The goal was to find the safest dose and see if the combination can control the disease. Participants had either newly diagnosed o…

This early-stage study tested a drug called flotetuzumab in 3 adults whose acute myeloid leukemia (AML) came back after a stem cell transplant. The main goal was to see if the drug is safe and find the best dose. Researchers also looked at whether the drug could help control the …

This study tested a combination of three drugs (low-dose cytarabine or azacitidine, plus venetoclax and quizartinib) in 113 adults aged 60 and older with newly diagnosed acute myeloid leukemia (AML) who could not receive standard chemotherapy. The goal was to quickly control the …

This study looked at whether eating less fat and more fiber can lower the chance of a repeat Clostridioides difficile infection in people being treated for cancer. Eight patients with leukemia, lymphoma, or other cancers who had a recent C. diff infection took part. Researchers t…

This study looked back at 621 children in Denmark who had chemotherapy for acute leukemia between 2008 and 2022. Researchers wanted to find out how many got serious mold infections, how many died from them, and what made some children more likely to get infected. The goal is to b…