LEIOMYOSARCOMA
Clinical trials for LEIOMYOSARCOMA explained in plain language.
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Virus + radiation combo tested to shrink tough sarcoma tumors before surgery
Disease control OngoingThis study is testing a two-part treatment for soft tissue sarcoma before surgery. First, a modified cold sore virus (T-VEC) is injected into the tumor to help the immune system attack it. Then, patients receive radiation therapy. The goal is to kill as much of the tumor as possi…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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Scientists test new drug cocktails in fight against tough cancers
Disease control OngoingThis study is testing two different drug combinations to see how they affect advanced cancers that have stopped responding to standard treatments. It will enroll about 90 people with specific types of advanced colorectal cancer, pancreatic cancer, or a soft tissue sarcoma. The ma…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Two-Drug combo tested for Tough-to-Treat rare cancer
Disease control OngoingThis study is testing whether combining two drugs, rucaparib and nivolumab, can help control advanced leiomyosarcoma (LMS), a rare type of cancer. It is for adults whose cancer has spread or cannot be removed by surgery and who have tried 1 to 3 other treatments. The main goal is…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New hope for tough sarcomas: adding a targeted drug to standard treatment
Disease control OngoingThis study is for patients with newly diagnosed, high-risk soft tissue sarcomas that can be removed by surgery. It tests whether adding a drug called pazopanib to standard pre-surgery treatments (radiation with or without chemotherapy) helps shrink tumors more effectively and imp…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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New Two-Pronged attack tested against rare cancers before surgery
Disease control OngoingThis early-stage study is testing the safety of combining two immunotherapy drugs, nivolumab and BO-112, given before surgery for patients with operable soft tissue sarcoma. The goal is to see if stimulating the immune system to attack the tumor before it is removed can improve o…
Matched conditions: LEIOMYOSARCOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC