Experimental combo aims to boost immune attack on sarcoma before surgery
NCT ID NCT04420975
First seen Mar 24, 2026 · Last updated Jun 17, 2026 · Updated 11 times
Summary
This early-phase study tests the safety of combining two immunotherapy drugs—nivolumab and BO-112—given before surgery for soft tissue sarcoma that can be removed. About 14 adults with certain sarcoma types will receive these drugs to see if they help the immune system fight the tumor more effectively. The main goal is to check for side effects and measure immune changes in the tumor tissue after treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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