KRAS G12C MUTATION
Clinical trials for KRAS G12C MUTATION explained in plain language.
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New hope for hard-to-treat colon cancer: targeted drug duo shows promise
Disease control ENROLLING_BY_INVITATIONThis study tests two drug combinations for people with advanced colorectal cancer that has a specific genetic change called KRAS G12C. In one group, patients who haven't had treatment before will get the drugs IBI351 and cetuximab plus chemotherapy. In another group, patients who…
Matched conditions: KRAS G12C MUTATION
Phase: PHASE2 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 26, 2026 06:16 UTC
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Personalized medicine takes on brain tumors: Gene-Targeted drugs show promise
Disease control OngoingThis study tests whether genetic testing can help doctors choose the right drug for people whose cancer has spread to the brain. Researchers will look for specific gene changes in tumor samples and then give patients a targeted medication matched to their mutation. The goal is to…
Matched conditions: KRAS G12C MUTATION
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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Scientists dig into genetic secrets of Drug-Resistant lung cancer
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at why certain lung cancers stop responding to targeted therapy (tyrosine kinase inhibitors). Researchers will analyze tumor tissue from 40 patients to find hidden genetic changes that cause drug resistance. The goal is to uncover new ways to treat these resistan…
Matched conditions: KRAS G12C MUTATION
Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC