KNEE OSTEOARTHRITIS (OA)
Clinical trials for KNEE OSTEOARTHRITIS (OA) explained in plain language.
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Knee arthritis study tests if painkillers ruin sugar injection therapy
Symptom relief Recruiting nowThis study looks at whether taking ibuprofen (a common painkiller) changes how well dextrose prolotherapy (sugar-water injections) works for knee osteoarthritis. About 68 adults aged 45-75 with knee arthritis will get three injections over 8 weeks, plus either ibuprofen or a plac…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: PHASE2 • Sponsor: David Grant U.S. Air Force Medical Center • Aim: Symptom relief
Last updated May 26, 2026 06:02 UTC
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Could a daily growth hormone shot ease your knee pain?
Symptom relief Recruiting nowThis early-stage study tests whether a daily injection of recombinant human growth hormone (rHGH) can help people with knee osteoarthritis. 34 adults aged 18-65 with knee OA for over 6 months will self-inject either the hormone or a placebo for 6 weeks. The main goal is to see if…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: PHASE1, PHASE2 • Sponsor: Dr. David Wasserstein • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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New study tests natural supplement for knee pain relief
Symptom relief Recruiting nowThis study tests whether a natural supplement called Native CT-II (a type of collagen) can reduce pain and improve knee function in people with knee osteoarthritis. About 114 adults aged 40-65 with moderate knee pain will take the supplement, a standard joint supplement, or a pla…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: NA • Sponsor: Vedic Lifesciences Pvt. Ltd. • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Weekly shot could shed pounds and ease knee pain for millions
Symptom relief Recruiting nowThis study tests a once-weekly injection called NNC0487-0111 in 400 adults with overweight or obesity and knee osteoarthritis. Half get the drug, half get a placebo. Researchers will measure weight loss and changes in knee pain and function over time. The goal is to see if the dr…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Phase: PHASE3 • Sponsor: Novo Nordisk A/S • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New registry to see if blocking knee arteries eases arthritis pain
Knowledge-focused Recruiting nowThis study is creating a registry of up to 100 adults with knee osteoarthritis to track how well a procedure called genicular artery embolization (GAE) reduces pain over 12 months. Participants have had knee pain for over 6 months that hasn't improved with standard treatments lik…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated May 26, 2026 05:57 UTC
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Researchers seek clues to knee pain mysteries
Knowledge-focused Recruiting nowThis observational study looks at why some people with knee osteoarthritis feel more pain than others, even when their knee damage looks similar. About 300 adults aged 45-80 with chronic knee pain will complete surveys, walking tests, knee X-rays and MRIs, brain scans, and sensor…
Matched conditions: KNEE OSTEOARTHRITIS (OA)
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC