KIDNEY NEOPLASMS

This study tests the drug vorolanib in people with advanced kidney cancer that cannot be removed by surgery or has spread. It is for patients who need a second treatment after the first one stopped working. The goal is to see how long the drug controls the cancer and what side ef…

This study is testing a new ultrasound technique called Contrast Enhanced Super-Resolution (CESR) imaging to see if it can better find and tell apart cancerous and non-cancerous lesions in the breast, liver, and kidney. About 40 people will take part, including 10 healthy volunte…

This study aims to see if a new imaging agent called [18F]RCCB6 can improve PET/CT scans for diagnosing kidney cancer, especially the most common type (clear cell renal cell carcinoma). About 300 adults with confirmed or suspected kidney cancer will receive the agent and undergo …

This study looks at a rare inherited condition called Birt-Hogg-Dube (BHD) syndrome, which raises the risk of kidney cancer. Researchers want to learn more about the genes involved, how kidney tumors grow, and the overall risk for people with BHD. Up to 950 people with known or s…

This study looks at whether a blood test that detects tiny bits of tumor DNA can help monitor kidney cancer after surgery. Researchers will follow 450 people with newly diagnosed kidney cancer who have surgery to remove the tumor. The goal is to see if this test can predict cance…

This study aims to find the genes that cause pheochromocytoma and paraganglioma, rare tumors of the nervous system. Researchers will analyze DNA from up to 2,000 patients and their family members to link specific genetic changes to tumor development. The goal is to improve geneti…