IRRITABILITY
Clinical trials for IRRITABILITY explained in plain language.
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AI coach for parents: new study tests virtual assistant for child behavior issues
Symptom relief Recruiting nowThis study tests whether adding an AI app to standard parenting classes helps families with children aged 5-12 who have disruptive behaviors like irritability or ADHD. About 40 parents will take 8 weekly online classes, with half also getting 24/7 AI support. Researchers will che…
Matched conditions: IRRITABILITY
Phase: NA • Sponsor: Fundació Sant Joan de Déu • Aim: Symptom relief
Last updated May 18, 2026 12:10 UTC
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New hope for cranky kids: therapies target severe temper outbursts
Symptom relief Recruiting nowThis study tests two psychological treatments—Cognitive Behavioral Therapy (CBT) and Interpretation Bias Training (IBT)—to reduce severe irritability in children aged 8 to 17 with Disruptive Mood Dysregulation Disorder (DMDD). Participants may choose one or both therapies. CBT in…
Matched conditions: IRRITABILITY
Sponsor: National Institute of Mental Health (NIMH) • Aim: Symptom relief
Last updated May 07, 2026 18:42 UTC
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Scientists scan brains to unlock the mystery of frustration
Knowledge-focused Recruiting nowThis study looks at how the brain responds when people feel frustrated. Researchers will use brain scans (MRI and MEG) while healthy adults aged 18 to 55 do a simple computer task. The goal is to understand the brain circuits involved in frustration, which may help develop better…
Matched conditions: IRRITABILITY
Phase: EARLY_PHASE1 • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 26, 2026 09:40 UTC
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Antidepressant's effect on anger in healthy youth under study
Knowledge-focused Recruiting nowThis study looks at how the antidepressant fluoxetine changes the way healthy young people (ages 18-24) process anger. Participants take either fluoxetine or a placebo daily for 7 days and complete tasks involving angry faces, words, and frustrating situations. The goal is to und…
Matched conditions: IRRITABILITY
Phase: NA • Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated May 26, 2026 09:39 UTC
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Brain scans may reveal which kids with ADHD will benefit from meds for anger and irritability
Knowledge-focused Recruiting nowThis study aims to find brain markers that can predict whether stimulant medication will help reduce irritability and aggression in children with ADHD. About 136 children with ADHD and high levels of irritability or aggression will take part. Researchers will measure brain activi…
Matched conditions: IRRITABILITY
Phase: PHASE4 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC