Irreversible pulpitis with apical periodontitis
Clinical trials for Irreversible pulpitis with apical periodontitis explained in plain language.
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Could a blood extract replace the root canal?
Disease control CompletedThis study tested whether using a patient's own platelet-rich plasma (PRP) inside a damaged tooth could reduce pain and improve healing better than a standard root canal. Forty-one adults with infected mature teeth were treated and followed for six months. The goal was to see if …
Matched conditions: IRREVERSIBLE PULPITIS WITH APICAL PERIODONTITIS
Sponsor: HITEC-Institute of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Sound waves may soothe Post-Root-Canal pain
Symptom relief CompletedThis trial tests whether activating a bio-ceramic sealer with sonic energy, using either the Eddy sonic or AF max device, reduces pain after root canal treatment. Researchers will compare these two sonic methods against standard sealer placement without activation. The study incl…
Matched conditions: IRREVERSIBLE PULPITIS WITH APICAL PERIODONTITIS
Sponsor: Future University in Egypt • Aim: Symptom relief
Last updated Sep 04, 2026 00:00 UTC
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Could probiotics ease tooth pain after root canal?
Symptom relief CompletedThis study tested whether probiotics, a double antibiotic paste, or calcium hydroxide paste can reduce pain after root canal treatment in adults with severe tooth inflammation (irreversible pulpitis). 75 participants received one of the three pastes placed inside the tooth and re…
Matched conditions: IRREVERSIBLE PULPITIS WITH APICAL PERIODONTITIS
Sponsor: Dow University of Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC