Sound waves may soothe Post-Root-Canal pain
NCT ID NCT06640218
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This trial tests whether activating a bio-ceramic sealer with sonic energy, using either the Eddy sonic or AF max device, reduces pain after root canal treatment. Researchers will compare these two sonic methods against standard sealer placement without activation. The study includes 30 adults with a painful lower first molar that has irreversible pulpitis and apical periodontitis. Participants will report their pain levels and how many painkillers they need after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sonic activation of a bio-ceramic sealer using either the Eddy sonic device or the AF max device during root canal treatment
- What this could lead to
- If sonic activation works, it could offer a simple way to reduce pain and the need for painkillers after root canal treatment.
- What could go wrong
- This is a small early-stage trial with only 30 participants, so results may not apply widely. The devices might not ease pain more than standard sealer placement.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age range is from 18 to 40 years old. * No sex predilection * Patients seeking root canal treatment. * restorable teeth. * Positive patient acceptance for participating in the study. * patients able to sign informed consent. * Systematically healthy patient (ASA I, Il). * Patient who can understand the numerical rate scale and sign an informed consent. * Mandibular first molar teeth with pain on bite or percussion * Preoperative sharp (moderate or severe) pain. * Vital response of pulp tissue to cold pulp tester (ethyl chloride spray). * widening in periodontal membrane space in radiographic appearance. Exclusion Criteria: * Patients with American Association of Anesthesiologists (ASA) classifications other than ASA 1 \& Il * Patients who have already ingested preoperative medication, such as analgesics, non-steroidal, or steroidal anti-inflammatory drugs, within 12 hours of the start of treatment. * This was done to prevent any misinterpretation of the diagnosis or post-treatment pain severity, as these drugs substantially lower post-endodontic pain (Jorge-Arajo et al.,2018). * Patients with NSAID allergy. * Patients having two or more adjacent teeth needing root canal therapy * Pregnant patients. * Patients with bleeding disorder. * Patients with long-term corticosteroid use. * Teeth having: * Necrotic pulp. * History or presence of swelling or fistulous tract. * Acute/chronic periapical abscess. * Mobility more than grade 1. * Pocket depth of more than 5mm * No possible restorability. * Previous root canal treatment. * Periapical radiolucency. * External or internal resorption * Vertical root fracture. * TMJ problems, bruxism, clenching or traumatic occlusion. * Inability to understand and perform the given instructions.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Future University in Egypt
Cairo, New Cairo, 11835, Egypt
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