INTERSTITIAL LUNG DISEASE (ILD)

This study tests whether tetrandrine tablets can improve lung function in adults with interstitial lung disease caused by connective tissue disease (like lupus or scleroderma). About 100 participants will take either tetrandrine or a placebo for 24 weeks, alongside their usual me…

This study looks at whether using a heart-lung machine (ECMO) routinely during lung transplants is better than using it only when necessary. About 218 people getting a lung transplant will take part. The goal is to find out which approach reduces time in the ICU and improves reco…

This study tests a new inhaled drug, mosliciguat, added to an existing treatment (treprostinil) for people with high blood pressure in the lungs caused by scarring lung disease. About 20 adults will take part to see if the combination is safe and tolerable. The goal is to manage …

This study tests whether using a robot to guide a lung biopsy helps doctors get clearer tissue samples for diagnosing interstitial lung disease (ILD). About 30 adults with suspected ILD will be randomly assigned to either standard bronchoscopy or robotic-assisted bronchoscopy. Th…

This study tests whether an artificial intelligence (AI) tool that reads electrocardiograms (ECGs) can help doctors find undiagnosed pulmonary hypertension in people with interstitial lung disease. About 900 adults with severe lung scarring will be randomly assigned to have their…

This study tests whether L-menthol, a minty compound, can reduce breathlessness and help people with interstitial lung disease (ILD) exercise longer. Twenty adults with ILD will try L-menthol and a placebo in random order to compare effects. The goal is to find a simple, safe way…

This early-stage study tests a single inhaled dose of RJ026 in 42 healthy volunteers and 42 people with interstitial lung disease (ILD). The goal is to measure how the drug moves through the body and check for side effects, not to treat the disease. Participants receive one of th…

This study tests whether bundling key tests (like CT scans and lung function tests) into a single, coordinated appointment can speed up diagnosis for people with suspected interstitial lung disease. Researchers will compare this streamlined approach to the usual, often fragmented…

This study tests a new way to manage follow-up care for people with interstitial lung disease (ILD). Instead of making multiple trips for tests and doctor visits, patients in the optimized group get everything done in one coordinated hospital visit. The goal is to see if this red…

This study looks at whether people with pulmonary fibrosis can use home monitoring and video calls instead of half their regular clinic visits. The goal is to see if this helps patients manage their own health better. About 220 adults with pulmonary fibrosis will take part, and r…