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New hope for rare lung disease: JAK inhibitors vs standard care

NCT ID NCT07406932

First seen Feb 15, 2026 · Last updated Jun 14, 2026 · Updated 28 times

Summary

This study tests whether JAK inhibitors work better than calcineurin inhibitors as the first treatment for lung scarring in people with antisynthetase syndrome. About 80 adults with active lung disease will be followed for 12 months to see which drug improves breathing and survival more. The goal is to give doctors clearer guidance on the best starting therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China-Japan Friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

antisynthetase syndrome interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.