Intensive care (ICU)

This phase III trial asks whether giving dexamethasone early to adults with severe influenza pneumonia and low blood oxygen can improve outcomes. Participants in intensive or intermediate care receive either the steroid or a placebo for up to 10 days, alongside standard flu treat…

This study looks at whether a quick lab test (multiplex PCR) can help doctors pick the right antibiotics faster for ICU patients with ventilator-associated pneumonia. About 170 adults on ventilators will be randomly assigned to get either the rapid test or standard testing. The g…

This study will test whether a bedside ultrasound can accurately confirm that a feeding tube is in the right place in ICU patients, compared to the standard chest X-ray. Researchers will enroll 170 adults in the ICU who need a feeding tube. If ultrasound works well, it could mean…

This study tests whether a short education program can help ICU patients on non-invasive ventilation (a breathing mask) use their machine more regularly and feel less anxious or depressed. About 92 adults will be randomly assigned to either the special training or standard care. …

This study looks at whether giving critically ill patients on breathing machines less protein (0.6-0.8 g/kg per day) during their early ICU stay leads to a better quality of life after leaving the hospital, compared to the standard amount (1.3 g/kg per day). About 1,026 adults wi…

This study tests whether continuous glucose monitors (CGMs) like the Dexcom G7 can be safely and effectively used in intensive care units. The monitors provide real-time blood sugar readings and alarms for dangerously high or low levels, potentially reducing the need for frequent…

This international study will track how tracheostomies—breathing tubes placed in the windpipe—are inserted, managed, and removed in adult intensive care units (ICUs) across the globe. By observing the care of thousands of patients, researchers hope to uncover variations in practi…

This study investigates whether the number of available beds in an intensive care unit (ICU) influences decisions to admit patients. Researchers will review records from 1,500 patients admitted to a postoperative ICU, comparing their severity of illness scores with bed availabili…

This study looks at whether a new, carefully designed plan for giving painkillers and sedatives to patients on ECMO (a life-support machine) is possible to use in hospitals. ECMO patients often face long-term problems like anxiety and memory issues, which may be linked to how muc…

This study looks at how the blood thinner enoxaparin works in critically ill ICU patients with kidney failure, some on dialysis and some not. Researchers will measure drug levels in the blood over 24 hours after a daily shot. The goal is to see if current dosing is enough to prev…

This study looks at how migrants with low income or unstable living situations experience being in the intensive care unit (ICU) and their recovery afterward. Researchers will interview 100 patients in France to understand their views and feelings about their health and hospital …