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New rapid test could slash unnecessary antibiotic use in ventilator pneumonia patients

NCT ID NCT07267624

Disease control Sponsor: University Hospital, Geneva Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a quick lab test (multiplex PCR) can help doctors pick the right antibiotics faster for ICU patients with ventilator-associated pneumonia. About 170 adults on ventilators will be randomly assigned to get either the rapid test or standard testing. The goal is to see if the rapid test reduces the time patients spend on strong, broad-spectrum antibiotics, which may lower side effects and antibiotic resistance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 170 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥ 18 years old) * Hospitalized in intensive care with invasive mechanical ventilation ≥ 48 hours * Administration of antimicrobial therapy for suspected VAP at the time of inclusion. * Expected survival \> 96 hours. Exclusion Criteria: * Enrollment prior to the current trial * Participation in an interventional study on the management of AMR that has a direct impact on antibiotic therapy practices.

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Conditions

The condition(s) this trial relates to.

Pneumonia, Ventilator-Associated respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antibiotic Antibiotic prescribing for acute respiratory-tract infections Antibiotic stewardship Intensive care (ICU) Vap - ventilator associated pneumonia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dept. of Intensive Care Medicine, University hospital of Lausanne

    Lausanne, Switzerland

  • Division of Intensive care, Hospital of Lugano

    Lugano, Switzerland

  • Division of Intensive care, Hospital of Neuchâtel

    Neuchâtel, Switzerland

  • Division of Intensive care, University hospital of Sion

    Sion, Switzerland

  • University hospitals of Geneva, Division of Intensive Care

    Geneva, Canton of Geneva, 1205, Switzerland

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