Inflammatory bowel disease

This phase 1 trial tests the safety and tolerability of LMT503, an oral drug intended for inflammatory bowel disease, in healthy adults aged 18 to 65. Participants receive either LMT503 or a placebo in single or multiple ascending doses, with some also checking how food affects t…

This study tests whether a special liquid diet (elemental diet) can help adults with inflammatory bowel disease (IBD) feel better during a flare. The diet provides all nutrients in an easy-to-digest form. Researchers will track symptom changes and inflammation levels in 42 outpat…

This study will follow 100 adults with Crohn's disease, ulcerative colitis, or other IBD, plus their healthy relatives, for up to 3 years. Researchers will collect blood, stool, tissue samples, and imaging to track how immune cells and genetics change over time. The goal is to fi…

This study looks at whether it's safe to skip mechanical bowel preparation (the drink that cleans out your colon) before colon surgery. Currently, the best practice combines that drink with antibiotics to prevent infections. The trial will compare two groups: one getting the drin…

This study looks at the eating habits of 50 pregnant women with inflammatory bowel disease (IBD). Researchers want to see if better diet quality is linked to healthier pregnancies and baby growth. The goal is to find nutritional gaps and suggest better dietary advice for this gro…

This study looks at how weight and body mass index (BMI) change in people with inflammatory bowel disease (IBD) who are treated with biologic drugs. Researchers will track weight monthly and see if higher BMI leads to higher drug doses and costs. The goal is to understand the fin…

This study looks at how common muscle loss (sarcopenia) is in people with inflammatory bowel disease (IBD) using CT scans. Researchers want to see if muscle loss changes how well biologic treatments work. About 50 adults with IBD who have received biologic therapy will take part.

This study will test a new way to offer vaccines to vulnerable patients—those with chronic diseases or weakened immune systems—during hospital visits. Researchers will see if offering, prescribing, and giving vaccines in the hospital increases how many people get vaccinated. The …