Infective endocarditis
Clinical trials for Infective endocarditis explained in plain language.
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Pill power: could oral antibiotics replace IV drips for endocarditis?
Disease control CompletedThis study tested whether stable patients with a serious heart valve infection (endocarditis) could safely switch from intravenous (IV) antibiotics to oral amoxicillin pills. Over 300 adults participated. The goal was to see if the oral switch worked as well as continuing IV trea…
Matched conditions: INFECTIVE ENDOCARDITIS
Phase 3 • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Pill power: could oral antibiotics replace IVs for serious heart infections?
Disease control CompletedThis study tested whether patients with a serious heart valve infection (endocarditis) caused by staph bacteria could safely switch from intravenous (IV) antibiotics to oral pills after at least 10 days of IV treatment. The trial involved 162 adults with left-sided endocarditis. …
Matched conditions: INFECTIVE ENDOCARDITIS
Phase 3 • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New PET scan could spot hidden heart infections
Diagnosis CompletedThis study is testing whether a special PET/CT scan using gallium-68 citrate can more accurately diagnose infections in artificial heart valves. Researchers will compare the scan results with the standard diagnosis after 3 months. The study involves 40 adults with suspected valve…
Matched conditions: INFECTIVE ENDOCARDITIS
Phase 2 • Sponsor: University Hospital, Bordeaux • Aim: Diagnosis
Last updated Aug 29, 2026 00:00 UTC
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New imaging study aims to reduce misdiagnosis of heart valve infections
Knowledge-focused CompletedThis study involved 30 patients who had a transcatheter aortic valve replacement (TAVR). Researchers used a special PET/CT scan with a radioactive tracer to see how noninfected valves appear on imaging. The goal is to create a baseline pattern so doctors can better tell if a valv…
Matched conditions: INFECTIVE ENDOCARDITIS
Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC