IMPLEMENTATION SCIENCE

This study tests whether a low-barrier hepatitis C treatment program can help people in jail start and finish treatment more easily. Forty adults awaiting trial at the Rhode Island Department of Corrections will receive a 12-week course of the HCV medication Epclusa, and if relea…

This study tests a new way to help young people with HIV in Kenya move from teen clinics to adult care. About 1,920 youth and their healthcare workers will try a program called the Adolescent Transition Package, led by youth themselves. The goal is to see if this approach helps m…

This study tests a digital health program called Corrie Lipids in about 1,000 adults with high LDL cholesterol and elevated heart disease risk. Participants use a smartphone app, get clinician coaching, and have their care streamlined to help them reach cholesterol goals. The goa…

This study compares two programs designed to prevent delirium (sudden confusion) in older adults during a hospital stay. One program uses hospital staff, while the other also involves family members or care partners. The goal is to see which approach works better to reduce confus…

This study is developing and testing a web-based decision-support tool to help state leaders choose the best evidence-based programs for improving parent and child mental health. About 80 adult decision-makers involved in state child welfare policy will use the tool and provide f…

This study looks at whether a short, hands-on training program can help emergency department advanced practice providers (like physician assistants and nurse practitioners) get better at using heart ultrasound. About 75 providers will take part in simulation training and then use…

This study aims to help leaders in Oregon—like health officials, community groups, and policymakers—use up-to-date data to make better choices about substance use services. The goal is to improve how resources are allocated to prevent overdoses and support treatment. About 341 de…

This study looks at whether a 3-month virtual program called Choose to Move Replacement Ready is practical for people waiting for hip or knee replacement surgery due to osteoarthritis. About 60 participants will answer surveys and interviews about their activity, pain, and well-b…

This study tests whether a new process can help more older adults get a special health check-up before major surgery. The check-up, called a geriatric assessment, looks at overall health to help plan care. Researchers will compare how many people use the new process versus past p…

This study looks at whether a special matching tool helps nurses choose the right IV device for children. About 394 pediatric nurses will use the tool and record their choices. The goal is to see if it improves nurses' knowledge and reduces errors in selecting the best IV for eac…

This study aims to improve how quickly injured children receive care in Tanzania. Researchers will work with local health centers and hospitals to create a better system for assessing and treating these children. The study involves about 284 participants, including children, thei…

This study looks at whether a new, step-by-step care plan for children having mild to moderate asthma attacks can improve how quickly they get the right treatment. The plan is designed to help doctors and nurses work together better. About 249 children and their healthcare provid…

This study looks at whether giving ICU staff real-time feedback and having a dedicated nurse facilitator can increase the use of a set of proven practices (the ABCDEF bundle) for adults on breathing machines. About 8,100 patients across multiple ICUs will take part. The goal is t…