IGA VASCULITIS

This study tests a drug called ravulizumab in children aged 2 to 18 with a kidney disease called IgA nephropathy. The goal is to see if the drug can reduce protein in the urine, a sign of kidney damage, and help control the disease. Participants will receive the drug through an I…

This study tests an experimental drug called sparsentan in 67 children with certain kidney diseases that cause protein leakage in urine. The goal is to see if the drug safely reduces protein levels over 108 weeks. Participants take the drug once daily as a liquid or tablet, and r…

This study is for people with a type of skin inflammation called vasculitis that affects only the skin. It compares three standard treatments to see which works best. The goal is to control the disease and improve quality of life, not to cure it. About 90 adults will take part.

This study tracks women with vasculitis who become pregnant to better understand how the disease affects pregnancy and what outcomes occur. Participants fill out online surveys during each trimester. No treatments or medications are tested—the goal is simply to gather information…

This study collects existing tissue samples from 1,000 people with various forms of vasculitis, a group of rare blood vessel diseases. Researchers will analyze the samples along with health data to find genes and other factors that cause these conditions. The goal is to spark new…

This study looks at skin samples from 50 people with different types of vasculitis, a condition where blood vessels become inflamed. Researchers want to understand how the disease affects the skin at a molecular level. Participants must have a skin rash or sore caused by active v…