Idiopathic normal pressure hydrocephalus (INPH)
Clinical trials for Idiopathic normal pressure hydrocephalus (INPH) explained in plain language.
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Brain shunt surgery put to the test in Placebo-Controlled trial
Disease control CompletedThis study tests whether a brain shunt—a device that drains extra fluid—can improve walking and thinking in older adults with idiopathic normal pressure hydrocephalus (iNPH). One hundred participants will either receive an active shunt or a placebo procedure. The main goal is to …
Matched conditions: IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH)
Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Can a Brain-Zapping device restore steady steps and sharp thinking?
Symptom relief CompletedThis trial is testing a device called Neuclare, which stimulates the brain, to see if it can improve walking and thinking in people with idiopathic normal pressure hydrocephalus (iNPH), a condition that causes gait problems, memory issues, and sometimes incontinence. The study wi…
Matched conditions: IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH)
Sponsor: Deepsonbio • Aim: Symptom relief
Last updated Aug 26, 2026 00:00 UTC
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Can a simple drug help people with fluid on the brain walk better?
Symptom relief CompletedThis study tested whether the drug acetazolamide can improve walking in people with normal pressure hydrocephalus (NPH), a condition where excess fluid in the brain causes trouble walking, thinking, and bladder control. Fifty adults with NPH were randomly assigned to receive eith…
Matched conditions: IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH)
Phase 2 • Sponsor: Uppsala University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Brain drain: can shunt surgery reverse cognitive decline and frailty?
Knowledge-focused CompletedThis study follows people with idiopathic normal pressure hydrocephalus (iNPH) who are already scheduled for shunt surgery. Researchers measure changes in thinking skills and frailty one year after the procedure to identify which patients are most likely to improve. The goal is t…
Matched conditions: IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH)
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC