Idiopathic inflammatory myopathy
Clinical trials for Idiopathic inflammatory myopathy explained in plain language.
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Can a One-Time cell therapy reset the immune system in autoimmune disease?
Cure Not yet recruitingThis trial is testing an experimental treatment called CRT-402 for people with severe autoimmune diseases like lupus, scleroderma, and myositis that haven't improved with standard therapies. CRT-402 is a type of CAR-T cell therapy given by infusion that aims to deplete certain im…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Phase 1/2 • Sponsor: Myeloid Therapeutics • Aim: Cure
Last updated Aug 23, 2026 00:00 UTC
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Can a new pill ease muscle weakness in myositis?
Disease control Not yet recruitingThis phase III trial tests whether the oral drug nerandomilast can improve symptoms of idiopathic inflammatory myopathies, a group of rare autoimmune diseases that cause muscle weakness and inflammation. Adults with active myositis are randomly assigned to take nerandomilast or a…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Phase 3 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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HIV drug repurposed to fight muscle inflammation
Disease control Not yet recruitingThis study tests whether Maraviroc, a drug currently used for HIV, can reduce muscle inflammation and improve function in adults with myositis that hasn't responded to standard treatments. Ten participants will take a daily 300mg tablet for 12 weeks and undergo muscle biopsies an…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Phase 4 • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Engineered immune cells take aim at childhood autoimmune diseases
Disease control Not yet recruitingThis early-phase trial tests a single infusion of universal CAR-T cells (RD06-05) in 30 children and adolescents with severe autoimmune diseases, including lupus, scleroderma, and kidney inflammation. The cells are designed to target and calm overactive immune cells. The main goa…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Early phase 1 • Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Experimental CAR-T injection aims to tame autoimmune diseases
Disease control Not yet recruitingThis early-phase trial tests an injection called KSVCBD, a type of CAR-T cell therapy, in 60 adults with severe autoimmune diseases like lupus and scleroderma. The goal is to see if it's safe and to get a first look at whether it might help control the disease. Participants recei…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Early phase 1 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New mRNA shot aims to calm stubborn autoimmune diseases
Disease control Not yet recruitingThis early-phase study tests a new drug called WGb-0301 for people with autoimmune diseases (like lupus or autoimmune hepatitis) that haven't responded to standard treatments. The drug uses mRNA technology to target and clear certain immune cells (B cells) that are causing the di…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Early phase 1 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Immune system reset: CAR T-Cells take on autoimmune diseases
Disease control Not yet recruitingThis study tests a new treatment using CD19 CAR T-cells for people with severe autoimmune diseases that haven't improved with standard therapies. About 30 participants will receive a single dose of these engineered immune cells after chemotherapy. The goal is to see if it's safe …
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Phase 1/2 • Sponsor: Hebei Senlang Biotechnology Inc., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 15:19 UTC
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Massive Real-World study to track brain and nerve autoimmune disorders
Knowledge-focused Not yet recruitingThis study will follow 1,550 adults with various neurological autoimmune diseases—like multiple sclerosis, myasthenia gravis, and autoimmune encephalitis—to see how these conditions progress and respond to treatments in everyday medical practice. Researchers will measure disabili…
Matched conditions: IDIOPATHIC INFLAMMATORY MYOPATHY
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC